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No improvement in outcomes with rapid, high-sensitivity troponin T testing protocol at one year

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Using more sensitive and frequent repeat testing of a blood test that indicates heart injury to guide the treatment of low-risk patients with symptoms of a possible heart attack resulted in patients being discharged earlier and receiving fewer cardiac stress tests but did not improve patient outcomes after one year, according to research presented at the American College of Cardiology s 70th Annual Scientific Session. In fact, a subset of patients receiving this more sensitive and frequent blood testing protocol were more likely to have a heart attack or to die during the one-year follow-up period compared with patients whose treatment was informed by the results of conventional blood testing procedures. ....

Flinders University , South Australia , Nicole Napoli , Yann Nguyen , Research Council Of Australia , National Health , American College Of Cardiology , American College , Annual Scientific , Derek Chew , Medical Research Council , Randomized Clinical Trial , Medicine Health , Clinical Trials , Critical Care Emergency Medicine , Death Dying , ஃப்லிஂடர்‌ஸ் பல்கலைக்கழகம் , தெற்கு ஆஸ்திரேலியா , நிக்கோல் ந்யாபலீ , ஆண்டு ஂக்யந் , ஆராய்ச்சி சபை ஆஃப் ஆஸ்திரேலியா , தேசிய ஆரோக்கியம் , அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல் , அமெரிக்கன் கல்லூரி , ஆண்டு அறிவியல் , டெரெக் மெல் ,

Clopidogrel superior to aspirin for long-term post-stent maintenance

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Clopidogrel outperformed aspirin in what is believed to be the first and largest randomized trial to compare the effectiveness of the two antiplatelet drugs as long-term maintenance therapy for patients who had no adverse events after one year of dual antiplatelet therapy (DAPT) following the insertion of a coronary stent. After two years of follow-up, chronic maintenance therapy with clopidogrel resulted in a 30% reduction in deaths, heart attacks, strokes or major bleeding events, according to research presented at the American College of Cardiology s 70th Annual Scientific Session.
These data confirm our working hypothesis that long-term maintenance antiplatelet monotherapy with clopidogrel produces better outcomes than aspirin in patients who are adverse event-free at one year after coronary stenting, said Hyo-Soo Kim, MD, PhD, professor of internal medicine at Seoul National University Hospital in South Korea and lead author of the study. ....

Soult Ukpyolsi , South Korea , Hyo Soo Kim , Nicole Napoli , Yann Nguyen , Antiplatelet Monotherapy , Seoul National University Hospital , American College Of Cardiology , Korean Ministry Of Health , American College , Annual Scientific , South Korean Ministry , Host Exam Randomized Controlled Trial , தெற்கு கொரியா , ஹயோ சூ கிம் , நிக்கோல் ந்யாபலீ , ஆண்டு ஂக்யந் , சியோல் தேசிய பல்கலைக்கழகம் மருத்துவமனை , அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல் , கொரியன் அமைச்சகம் ஆஃப் ஆரோக்கியம் , அமெரிக்கன் கல்லூரி , ஆண்டு அறிவியல் , தெற்கு கொரியன் அமைச்சகம் ,

De-escalation of dual antiplatelet therapy appears safe and effective

Among patients who had a cardiac stent inserted after a heart attack, switching to less-potent dual antiplatelet therapy (DAPT) after 30 days was safer and more effective in preventing adverse events a year later than continuing on a high-potency DAPT regimen, according to data presented at the American College of Cardiology s 70th Annual Scientific Session. ....

Soult Ukpyolsi , South Korea , Chong Kun Dang Pharm , Nicole Napoli , Yann Nguyen , Kiyuk Chang , Division Of Internal Medicine , American College Of Cardiology , Catholic University Of Korea , American College , Annual Scientific , Internal Medicine , Catholic University , East Asia , East Asian , Chong Kun Dang , Medicine Health , Clinical Trials , Death Dying , Pharmaceutical Science , தெற்கு கொரியா , சோங் குன் டங் பார்ம் , நிக்கோல் ந்யாபலீ , ஆண்டு ஂக்யந் , பிரிவு ஆஃப் உள் மருந்து , அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல் ,

Apixaban not superior to standard care after TAVR

The blood thinner apixaban was not superior to standard of care following transcatheter aortic valve replacement (TAVR), according to findings from a new trial called ATLANTIS presented at the American College of Cardiology s 70th Annual Scientific Session. ....

France General , Nicole Napoli , Hospitalier Pitie , Yann Nguyen , Jean Philippe Collet , American College Of Cardiology , Bristol Myers Squibb Pfizer Alliance , American College , Annual Scientific , Cardiovascular Trials Initiatives , Organized Networks , Groupe Hospitalier , Lassistance Publique , Bristol Myers , Anti Xa Anticoagulation , Trans Aortic Valve Implantation , Aortic Stenosis , Randomized Atlantis Trial , Medicine Health , Clinical Trials , Death Dying , பிரான்ஸ் ஜநரல் , நிக்கோல் ந்யாபலீ , ஆண்டு ஂக்யந் , ஜீன் பிலிப் கோலட் , அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல் ,

Higher blood levels of omega-3 fatty acids from prescription fish oil showed no effect on CV events

Patients at high risk for cardiovascular events who had the highest levels of eicosapentaenoic acid (EPA) in their blood one year after taking daily omega-3 carboxylic acid, a prescription-grade fish oil, had similar rates of major cardiovascular events as people taking a corn oil placebo, according to a secondary analysis of the STRENGTH trial presented at the American College of Cardiology s 70th Annual Scientific Session. ....

Nicole Napoli , Yann Nguyen , Steven Nissen , American College Of Cardiology , American College , Annual Scientific , Cleveland Clinic , Acid Levels , Major Adverse Cardiovascular Outcomes , High Cardiovascular Risk , Marine Freshwater Biology , Fisheries Aquaculture , Nutrition Nutrients , Medicine Health , Clinical Trials , Death Dying , நிக்கோல் ந்யாபலீ , ஆண்டு ஂக்யந் , ஸ்டீவன் நிசென் , அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல் , அமெரிக்கன் கல்லூரி , ஆண்டு அறிவியல் , கிளீவ்லேண்ட் சிகிச்சையகம் , அமிலம் நிலைகள் , கடல் நன்னீர் உயிரியல் ,