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Purpose: This study intends to uncover a more thorough knowledge structure, research hotspots, and future trends in the field by presenting an overview of the relationship between stroke and gut microbiota in the past two decades. Method: Studies on stroke and gut microbiota correlations published between 1st January 2002 and 31st December 2021 were retrieved from the Web of Science Core Collection and then visualised and scientometrically analysed using CiteSpace V. Results: A total of 660 papers were included in the study, among which the USA, the UK, and Germany were the leading research ce...

Understanding the durability of the protection conferred by SARS-CoV-2 infection and vaccination is of utmost importance to guide COVID-19 mitigation policies worldwide. In November, 2021, before the emergence of the omicron (B.1.1.529) variant, an estimated 3·8 billion people (44% of the global population) had been infected by SARS-CoV-2.1 This number is likely to have exponentially increased with the spread of the omicron variant, the most transmissible SARS-CoV-2 variant to date, suggesting that most of the global population has now already experienced SARS-CoV-2 infection at least once.

The influenza A (N7N9) virus has been seriously concerned for its potential to cause an influenza pandemic. To understand the spread and evolution process of the virus, a spatial and temporal Bayesian evolutionary analysis was conducted on 2,052 H7N9 viruses isolated during 2013 and 2018. It revealed that the H7N9 virus was probably emerged in a border area of Anhui Province in August 2012, approximately six months earlier than the first human case reported. Two major epicenters had been developed in the Yangtze River Delta and Peral River Delta regions by the end of 2013, and from where the v...

BioPharma

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits variable immunity responses among hosts based on symptom severity. Whether immunity in recovered individuals is effective for avoiding reinfection is poorly understood. Determination of immune memory status against SARS-CoV-2 helps identify reinfection risk and vaccine efficacy. Hence, after recovery from COVID-19, evaluation of protective effectiveness and durable immunity of prior disease could be significant. Recent reports described the dynamics of SARS-CoV-2 -specific humoral and cellular responses for more than six mon...