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Scientists identify immunogens that can elicit antibody responses against multiple SARS-CoV-2 variants

In a new study, researchers identified conserved sites in the SARS-CoV-2 spike protein using structural and sequence data, and then combined the results with existing deep mutational scanning data to design six antigens that can offer protection against significant immune escape mutations in the SARS-CoV-2 receptor-binding domain. ....

Image Credit , Coronavirus Disease Covid 19 , Ars Cov 2 , Binding Affinity , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein ,

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

In the recently published study in The Lancet, first-authored by Dr. Sue Ann Costa Clemens from the University of Oxford in the United Kingdom and the University of Siena in Italy, a comprehensive analysis has been pursued on the immunogenicity and safety of both homologous and heterologous boosting after receiving the inactivated vaccine CoronaVac. ....

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COVID-19 vaccine does not lead to infertility in either men or women

In a recent prospective cohort study accepted to the American Journal of Epidemiology, researchers observed links between female and male coronavirus disease 2019 (COVID-19) vaccination and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and fecundability or the per-cycle likelihood of conception in North American couples seeking to conceive. ....

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SARS-CoV-2 Omicron variant found to display increased resilience to antiviral type I interferon response

In a new study, scientists have compared the Omicron variant with the Delta VOC (B.1.617.2) as well as the wildtype strain (B.1), with respect to their interaction with the antiviral type 1 interferon response in infected cells. ....

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Study suggests synthetic SARS-CoV-2 S glycoprotein coated lipid vesicles are an effective vaccine candidate

In a new study, a team of researchers developed a vaccine candidate with the SARS-CoV-2 spike (S) glycoprotein coated onto lipid vesicles which resembles virus-like particles. ....

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