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Clinical trial of monoclonal antibody for treating respiratory disease in COVID-19 patients begins


Clinical trial of monoclonal antibody for treating respiratory disease in COVID-19 patients begins
A clinical trial testing the safety and efficacy of an investigational monoclonal antibody for treating people who are hospitalized with respiratory disease and low blood oxygen due to infection with SARS-CoV-2, the virus that causes COVID-19, has begun. The Phase 2 trial, called the COVID-19 anti-CD14 Treatment Trial (CaTT), is sponsored and funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
The laboratory-created monoclonal antibody, called IC14, binds to a human protein, CD14, that is found on the surface of immune cells circulating in the blood and airway fluid and that also circulates as a stand-alone protein. CD14 helps immune cells recognize pathogens and injured or dying cells, alerting the immune system to danger and prompting it to respond. ....

Vanderbilt University , United States , Foster City , Markm Wurfel , Thomasr Martin , Anthonys Fauci , Emily Henderson , National Institute Of Allergy , National Institutes Of Health , Vanderbilt University In Nashville , Gilead Sciences Inc , Division Of Pulmonary , Tolerance Network , Medicine At University Of Washington , Implicit Bioscience Ltd , National Institute , Infectious Diseases , National Institutes , Critical Care , Sleep Medicine , Immune Tolerance Network , Implicit Bioscience , Gilead Sciences , Respiratory Disease , Clinical Trial , Immune Response ,

NIH begins trial of antibody for Covid-19 linked respiratory disease


NIH begins trial of antibody for Covid-19 linked respiratory disease 
14th April 2021 (Last Updated April 14th, 2021 12:37)
The National Institutes of Health (NIH) has initiated a Phase II clinical trial of an investigational monoclonal antibody IC14 for treating hospitalised Covid-19 patients with respiratory disease and low blood oxygen. 
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Colourised scanning electron micrograph of a cell (pink) infected with SARS-CoV-2 virus particles (teal), isolated from a patient sample. Credit: NIAID.
The National Institutes of Health (NIH) has initiated a Phase II clinical trial of an investigational monoclonal antibody IC14 for treating hospitalised Covid-19 patients with respiratory disease and low blood oxygen. ....

Anthony Fauci , Tolerance Network , Gilead Sciences , National Institutes Of Health , National Institute Of Allergy , National Institutes , National Institute , Infectious Diseases , Immune Tolerance Network , Implicit Bioscience , சகிப்புத்தன்மை வலைப்பின்னல் , கிலியட் அறிவியல் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , தேசிய நிறுவனம் ஆஃப் ஒவ்வாமை , தேசிய நிறுவனங்கள் , தேசிய நிறுவனம் , தொற்று நோய்கள் , நோய் எதிர்ப்பு சக்தி சகிப்புத்தன்மை வலைப்பின்னல் ,