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In this MEDcast episode, Diana Isaacs, PharmD, BC-ADM, CDCES, and Natalie Bellini, DNP, FNP-BC, interview Dr Juan Frias to explore the mechanism of GLP-1 and GIP agonists in diabetes and weight management and examine key findings from clinical trials for the latest GLP-1/GIP dual agonist. ....
Doctors and researchers have been trying to end the obesity epidemic for decades and have failed. Can a new set of effective drugs finally succeed? Second in a 3-part series on the obesity crisis. ....
Tirzepatide s agonist effect on GIP receptors of isolated pancreatic islet cells appears responsible for a good portion of the drug s effects beyond its GLP-1 receptor agonism. ....
Over 60% of participants achieved the weight-reduction target of 20% or higher and had improved body composition in a phase 3 trial of tirzepatide in overweight/obesity. ....
A combination of a swallowable Allurion gastric balloon and liraglutide delivers higher weight loss (around 19% after mean 4 months) than use of separate treatments. ....