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Researchers discover new mechanism involved in early melanoma metastasis

“We must not only look inside the tumour but also outside of it,” says Héctor Peinado, a researcher at the Spanish National Cancer Research Centre ....

New York , United States , David Lyden , Susana Garcia Silva , Babak Mehrara Memorial Sloan Kettering Cancer Center , Institute Of Health Carlos , Spanish Association , Starr Cancer Consortium , Microenvironment Metastasis Group , Michelle Levesque University Of Zurich Hospital , Areces Foundation , European Regional Development Fund , Spanish Ministry Of Science , Feldstein Foundation , Community Of Madrid , Caixa Foundation , Melanoma Research Alliance , Spanish National Cancer Research Centre , Us National Institutes Of Health , Uri Saragovi Mcgill University , Metastasis Group , Nature Cancer , Piotr Rutkowski , Michelle Levesque , Zurich Hospital , Uri Saragovi ,

New optical technique for remote detection of viruses on surfaces

New optical technique for remote detection of viruses on surfaces
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

Spain General , Emily Henderson , Institute Of Health Carlos , Spanish Ministry , Research Centre , Health Institute , Group Of The Spanish National Police , Andalusian Network For The Design , Universidad De Sevilla University Of Seville , Andalusian Technological Corporation , German Astronomical Center Calar Alto Observatory , Engineering School At Universidad De Sevilla , Seville University , University Of Seville , Nature Publishing Group , European Commission , Interdisciplinary Physics Group , Institute Of Astrophysics Andalusia , Virgen Macarena University Hospitals In Seville , Group Of Applied Neuroscience , Institute Of Biomedicine Seville , Universidad De Sevilla , Calar Alto , Scientific Reports , Explosive Ordnance Disposal , Spanish National Police ,

Study elucidates the role of two isoforms of KRAS oncogenes

Study elucidates the role of two isoforms of KRAS oncogenes
KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common drivers of cancer and its mutations can be detected in around 25 per cent of human tumors. The development of KRAS inhibitors is, thus, an extremely active line of research. Effective results have been elusive so far, though - no KRAS inhibitor had been available until a month ago, when the FDA granted approval to Sotorasib.
KRAS encodes two gene products, KRAS4A and KRAS4B, whose levels can vary across organs and embryonic stages. When KRAS mutates, both variants, or isoforms, are activated. Though, some studies have focussed on approaches to target only KRAS4B, since it usually found to be expressed at higher levels in tumors. ....

Mariano Barbacid , Eduardo Caleiras , Marina Salm , Matthias Drosten , Sagrario Ortega , Guillem Paniagua , Emily Henderson , Autonomous Community Of Madrid , Institute Of Health Carlos , Experimental Oncology Group , Spanish Ministry Of Science , European Research Council , Research Fund , Experimental Oncology Programme , Oncology Group , Mouse Genomic Editing Core Unit , Score Unit , Histopathology Core Unit , Spanish Ministry , Health Carlos , Autonomous Community , எமிலி ஹென்டர்சன் , தன்னாட்சி சமூக ஆஃப் மாட்ரிட் , நிறுவனம் ஆஃப் ஆரோக்கியம் கார்லோஸ் , சோதனை புற்றுநோயியல் குழு , ஸ்பானிஷ் அமைச்சகம் ஆஃப் அறிவியல் ,

CNIO researchers clarify the role of the two isoforms of KRAS, the most common oncogene in humans

CNIO researchers clarify the role of the two isoforms of KRAS, the most common oncogene in humans
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Mariano Barbacid , Eduardo Caleiras , Marina Salm , Matthias Drosten , Sagrario Ortega , Guillem Paniagua , Autonomous Community Of Madrid , Institute Of Health Carlos , Experimental Oncology Group , Spanish Ministry Of Science , European Research Council , Research Fund , Experimental Oncology Programme , Oncology Group , Mouse Genomic Editing Core Unit , Score Unit , Histopathology Core Unit , Spanish Ministry , Health Carlos , Autonomous Community , தன்னாட்சி சமூக ஆஃப் மாட்ரிட் , நிறுவனம் ஆஃப் ஆரோக்கியம் கார்லோஸ் , சோதனை புற்றுநோயியல் குழு , ஸ்பானிஷ் அமைச்சகம் ஆஃப் அறிவியல் , ஐரோப்பிய ஆராய்ச்சி சபை , ஆராய்ச்சி நிதி ,

Hospitalizada por un caso "sospechoso" de fiebre Crimea-Congo tras la picadura de una garrapata

Hospitalizada por un caso "sospechoso" de fiebre Crimea-Congo tras la picadura de una garrapata
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Castillay Leóp , Health Carlos , Institute San Karl Madrid , Hospital River , Medical Sources Told , Salamanca Second , Teaching Hospital River Hortega , Hospital Hortega , Institute Of Health Carlos , ஆரோக்கியம் கார்லோஸ் , நிறுவனம் ஆஃப் ஆரோக்கியம் கார்லோஸ் ,