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NIH funds $12.5 million initiative to create the world's first integrated pancreas knowledgebase

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health to create the world's first, integrated knowledgebase of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research. ....

United States , Xujing Wang , Ben Voight , Stephen Parker , Marcela Brissova , Ashley Xia , Anna Gloyn , Knowledgebase Pankbase , Kyle Gaulton , Knowledgebase Genomic , Diane Saunders , Michael Stitzel , Shuibing Chen , Jean Philippe Cartailler , Jie Liu , Jason Flannick , National Institute Of Diabetes , Common Fund Knowledge Center , Human Pancreas Analysis Program , University Of Michigan , University Of California San Diego , Human Islet Research Enhancement Center , Medicines Partnership , National Institutes Of Health , Human Islet Research Network , Common Fund ,

Protein Kdm1a plays a crucial role in preserving neuronal identity, study shows

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways. ....

Miguel Hern , Yijun Ruan , Angel Barco , Institute For Neurosciences , Spanish Research Agency , Nature Communications , Spanish National Research Council , Ministry Of Science , Jackson Laboratory For Genomic Medicine , Epigenetic Mechanisms , Neuronal Plasticity , Functional Epi Genomics , Del Blanco , Jackson Laboratory , Genomic Medicine , Cleft Palate , Psychomotor Delay , Distinctive Facial Features , Intellectual Disability , Spanish Research Agency Ministry ,

Protein Kdm1a's Role in Preserving Neuronal Identity Uncovered

Protein Kdm1a's Role in Preserving Neuronal Identity Uncovered
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Yijun Ruan , Angel Barco , Miguel Hern , Ministry Of Science , Spanish Research Agency , Nature Communications , Spanish National Research Council , Institute For Neurosciences , Jackson Laboratory For Genomic Medicine , Epigenetic Mechanisms , Neuronal Plasticity , Functional Epi Genomics , Beatriz Del Blanco , Jackson Laboratory , Genomic Medicine , Cleft Palate , Psychomotor Delay , Distinctive Facial Features , Intellectual Disability , Spanish Research Agency Ministry ,

Study reveals the role of the protein Kdm1a in maintaining neuronal identity

Neurons from the brain of an adult mouse in which chromatin (in blue), the nuclear envelope (in green), and silenced ....

Miguel Hern , Yijun Ruan , Angel Barco , Institute For Neurosciences , Nature Communications , Spanish National Research Council , Jackson Laboratory For Genomic Medicine , Instituto De Neurociencias , Epigenetic Mechanisms , Neuronal Plasticity , Functional Epi Genomics , Beatriz Del Blanco , Jackson Laboratory , Genomic Medicine , Del Blanco ,

The Jackson Laboratory and LG AI Research partner to pioneer biomedical advancements

The Jackson Laboratory and LG AI Research partner to pioneer biomedical advancements
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United States , Lon Cardon , Charles Lee , Paul Flicek , Kyunghoon Bae , Lg Group , Jackson Laboratory For Genomic Medicine , Jackson Laboratory , Lg Ai Research , National Cancer Center , Chief Data Science Officer , Genomic Medicine , Robert Alvine Family Endowed Chair ,