Most RA Patients Meet EMA's JAK Inhibitor Warning Criteria
Recent regulatory warnings could mean that four in five patients with RA may not be prescribed JAK inhibitors unless there is no other alternative.
Source: medscape.com
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EMA Reviewing Delgocitinib Cream for Chronic Hand Eczema
Delgocitinib is an investigational topical pan–Janus kinase inhibitor that inhibits activation of the JAK-STAT pathway.
Source: medscape.com
Evolving Treatment Armamentarium for Myelofibrosis
Key opinion leaders provide a broad perspective on the current treatment armamentarium available to patients diagnosed with myelofibrosis.
Source: onclive.com
MyJournals.org - Science - 'IJMS, Vol. 24, Pages 11187: KLF13 Regulates the Activity of the GH-Induced JAK/STAT Signaling by Targeting Genes Involved in the Pathway' (International Journal of Molecular Sciences)
MyJournals.org - Science - 'IJMS, Vol. 24, Pages 11187: KLF13 Regulates the Activity of the GH-Induced JAK/STAT Signaling by Targeting Genes Involved in the Pathway' (International Journal of Molecular Sciences)
Source: myjournals.org
EULAR PsA Update Emphasizes Safety, Non-MSK Manifestations
The update builds on 2019 recommendations and incorporates safety concerns about JAK inhibitors, advises on differential drug efficacy across disease manifestations, and eliminates systemic steroids.
Source: medscape.com