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E-Mail IMAGE: Three receptor tyrosine kinases (RTKs) EGFR (orange), HER2 (pink), and MET (green) are imaged before and after the use of a MET-selective tyrosine kinase inhibitor (Trametinib), and trametinib, a mitogen activated protein. view more Credit: Image created by Patricia Pereira, PhD, Research Associate at Memorial Sloan Kettering Cancer Center Reston, VA Immuno-positron emission tomography (PET) imaging can provide early insight into a tumor s response to targeted therapy, allowing physicians to select the most effective treatment for patients who have cancer. The new research was published in the March issue of The Journal of Nuclear Medicine. The research showed that immuno-PET successfully visualizes changes in different cancer receptors (receptor tyrosine kinases, or RTKs) within tumors during targeted therapies. This gives physicians a tool that can be used to evaluate the effectiveness of a treatment soon after its administration. ....
Credit: Society of Nuclear Medicine and Molecular Imaging. Reston, Virginia The Journal of Nuclear Medicine (JNM) has issued a special supplement commemorating six decades of leadership in the field of nuclear medicine, molecular imaging and therapy. The supplement features a collection of the most influential and frequently cited manuscripts in JNM s history, representing seminal discoveries and scientific contributions that shaped the future of medicine. Invited perspectives from world leaders in nuclear medicine, molecular imaging, and theranostics explain why each of these articles had such an enormous impact. Highlights include milestone articles on the invention of the Anger camera, the creation of positron emission tomography (PET) and 18F-FDG, the development of fusion PET/CT, the introduction of FDG PET-based response criteria in solid tumors, and many more landmark papers that have shaped the history of nuclear medicine. ....