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Hamilton is the ninth largest city in the vast expanse of Canada, while Mupandawana, having achieved town status only in 2014, is much less developed.

Using the freshest blood for transfusion may not necessarily improve patients survival rates, Canadian researchers have found.

The COVID-19 pandemic destabilised health-care systems and led to millions of excess deaths worldwide.1 Disproportionate inflammatory response and thromboembolic events denoted the clinical spectrum of patients with severe disease phenotypes and poor outcomes. In early 2020, when SARS-CoV-2 vaccines and antivirals such as nirmatrelvir–ritonavir were not yet available, approved immunomodulatory, immunosuppressive, and antithrombotic agents seemed inexpensive and safe options to treat patients in the community and hospital settings.

For less-sick patients, results from the ACT trials showed no benefits with colchicine, aspirin, or rivaroxaban plus aspirin.

It's 'the end of the story for colchicine in COVID-19,' an expert said. In addition, aspirin does not help outpatients with COVID and a low-dose oral anticoagulant does not improve inpatient outcomes.