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Dr Mascarenhas on the Use of Selinexor in Myelofibrosis

John Mascarenhas, MD, discusses the use of selinexor with ruxolitinib in JAK inhibitor–naive myelofibrosis, highlighting the phase 2 XPORT-MF-044 trial

John-mascarenhas , Tisch-cancer-institute , Icahn-school-of-medicine , Icahn-school , Mount-sinai , Blood-cancers , Myeloid-disorders , Onclive-tv , Reviewing-research-efforts-seeking-to-raise-the-bar-in-myelofibrosis ,

Shifting models of team care delivery : JAAPA

Shifting models of team care delivery : JAAPA
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Shifting models of team care delivery : JAAPA

Shifting models of team care delivery : JAAPA
lww.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from lww.com Daily Mail and Mail on Sunday newspapers.

United-states , American , John-mascarenhas , Kylea-farina , Michelle-becker , National-commission-on-certification-of-physician-assistants , Association-of-american-medical-colleges , American-academy-of-physician-associates , National-commission , Physician-assistants , American-medical-colleges , Medical-specialty

PAs in the cancer care continuum : JAAPA

PAs in the cancer care continuum : JAAPA
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One Woman's Journey to Help Control Her Polycythemia Vera | Health & Wellness

One Woman's Journey to Help Control Her Polycythemia Vera | Health & Wellness
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Geron Announces Fifty Percent Enrollment in the Phase 3 IMpactMF Clinical Trial Evaluating Imetelstat in Patients with Relapsed/Refractory Myelofibrosis

Geron Announces Fifty Percent Enrollment in the Phase 3 IMpactMF Clinical Trial Evaluating Imetelstat in Patients with Relapsed/Refractory Myelofibrosis
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Pelabresib Plus Jakafi Reduces Spleen Volume, Myelofibrosis Symptoms

Findings of MANIFEST-2 show “valuable evidence that the addition of pelabresib offers meaningful improvements over JAK inhibitor monotherapy as a first-line approach for patients with myelofibrosis,” according to one expert.



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Pelabresib Plus Ruxolitinib Improves Spleen Volume Reduction in JAK Inhibitor-Naive Myelofibrosis

Treatment with the combination of pelabresib and ruxolitinib led to a statistically significant and clinically meaningful improvement in spleen volume reduction vs placebo plus ruxolitinib in patients with JAK inhibitor-naive myelofibrosis, meeting the primary end point of the phase 3 MANIFEST-2 trial.

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