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"Christchurch Mutation" – How Good Can Overpower Evil in Alzheimer's Disease Genetics

New research sheds light on protective mechanisms of the “Christchurch mutation.” Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the “Christchurch mutation” can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most co ....

Universidad De Antioquia , New Zealand , United States , Reuben Thomas , Tenzing Choenyi , Josephf Arboleda Velasquez , Oscar Yip , Yakeelt Quiroz , Robertw Mahley , Eric Reiman , Jessica Blumenfeld , Seo Yeon Yoon , Robert Mahley , Maxiner Nelson , Michela Traglia , Joseph Arboleda Velasquez , Brian Grone , Joo Kim , Aayushi Agrawal , Maxine Nelson , Nicole Koutsodendris , Yanxia Hao , Yakeel Quiroz , Peng Liu , Francisco Lopera , Yadong Huang ,

Patient-Inspired Antibody Therapy Lessens Alzheimer's Tau Tangles

Patient-Inspired Antibody Therapy Lessens Alzheimer's Tau Tangles
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United States , Claudia Marino , Josephf Arboleda Velasquez , Journal Of The Alzheimer Association , Department Of Ophthalmology At Mass Eye , Mass General Brigham , Mass Eye , Massachusetts General Hospital ,

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease
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United States , Claudia Marino , Pixabay Pete Linforth , Josephf Arboleda Velasquez , Department Of Ophthalmology At Mass Eye , Mass General Brigham , Mass Eye , Massachusetts General Hospital ,