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Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

Study evaluates senolytic CAR T-cell therapy targeting uPAR-positive cells in aged mice, showing its effectiveness in mitigating age-related metabolic dysfunction and offering a potential long-lasting treatment for aging-associated conditions. ....

Juan Gaertner Shutterstock , Nature Aging , Juan Gaertner , Cart Cell , T Cell , Cell Cycle , Chimeric Antigen Receptor , Small Molecules , Wound Healing ,

Epigenetics in Drug Discovery: Modulating Gene Expression for Health

Understanding epigenetics gives healthcare professionals and researchers insights into the molecular processes that influence health and diseases, potentially leading to better disease prevention, early detection, and more targeted treatments. ....

Juan Gaertner Shutterstock , Changc Epigenetics , Paul Brennan , Genet Epigenet , Image Credit , Biomedical Science , Adv Exp Med ,

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

A new paper in The Lancet eBioMedicine explores whether these changes predict the future risk of stomach tumors and how epigenetic changes interact with environmental and lifestyle factors in this process. ....

Juan Gaertner Shutterstock , Early Disease Detection , Prevention Study , Na Methylation , Epstein Barr Virus , Gastric Cancer , Helicobacter Pylori , Stomach Cancer ,