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Potential HIV vaccine component leads to strong protection in primates

To block infection from HIV, a successful vaccine will require a combination of ingredients, including at least three antibody targets and a substance that boosts immune responses.

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Potential HIV Vaccine Component Proves Effective in Primate Study

To block infection from HIV, a successful vaccine will require a combination of ingredients, including at least three antibody targets and a substance that boos

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Scientists from UNC and Duke identify new antibody for COVID-19 and variants

CHAPEL HILL & DURHAM - A research collaboration between scientists at Duke University and the University of North Carolina at Chapel Hill has identified and

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Duke, UNC-Chapel Hill scientists identify new antibody for Covid and variants

DURHAM, N.C. and CHAPEL HILL, N.C. – A research collaboration between scientists at Duke University and the University of North Carolina at Chapel

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Duke study reveals mechanisms of increased infectivity, antibody resistance of SARS-CoV-2 variants

Duke study reveals mechanisms of increased infectivity, antibody resistance of SARS-CoV-2 variants
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Newly identified antibody can be targeted by HIV vaccines


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DURHAM, N.C. - A newly identified group of antibodies that binds to a coating of sugars on the outer shell of HIV is effective in neutralizing the virus and points to a novel vaccine approach that could also potentially be used against SARS-CoV-2 and fungal pathogens, researchers at the Duke Human Vaccine Institute report.
In a study appearing online May 20 in the journal
Cell, the researchers describe an immune cell found in both monkeys and humans that produces a unique type of anti-glycan antibody. This newly described antibody has the ability to attach to the outer layer of HIV at a patch of glycans -- the chain-like structures of sugars that are on the surfaces of cells, including the outer shells of viruses.

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Duke University: New Vaccine Blocks COVID-19 and Variants, Plus Other Coronaviruses


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A potential new vaccine developed by members of the Duke Human Vaccine Institute has proven effective in protecting monkeys and mice from a variety of coronavirus infections — including SARS-CoV-2 as well as the original SARS-CoV-1 and related bat coronaviruses that could potentially cause the next pandemic.
The new vaccine, called a pan-coronavirus vaccine, triggers neutralizing antibodies via a nanoparticle. The nanoparticle is composed of the coronavirus part that allows it to bind to the body’s cell receptors, and is formulated with a chemical booster called an adjuvant. Success in primates is highly relevant to humans.
The findings appear Monday, May 10 in the journal Nature.

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Duke scientists develop new potential coronavirus vaccine – it's already effective in animal studies


by Sarah Avery — May 10, 2021 .
DURHAM – A potential new vaccine developed by members of the Duke Human Vaccine Institute has proven effective in protecting monkeys and mice from a variety of coronavirus infections – including SARS-CoV-2 as well as the original SARS-CoV-1 and related bat coronaviruses that could potentially cause the next pandemic.
The new vaccine, called a pan-coronavirus vaccine, triggers neutralizing antibodies via a nanoparticle. The nanoparticle is composed of the coronavirus part that allows it to bind to the body’s cell receptors, and is formulated with a chemical booster called an adjuvant. Success in primates is highly relevant to humans.

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New vaccine blocks COVID-19 and variants, plus other coronaviruses


 E-Mail
DURHAM, N.C. - A potential new vaccine developed by members of the Duke Human Vaccine Institute has proven effective in protecting monkeys and mice from a variety of coronavirus infections -- including SARS-CoV-2 as well as the original SARS-CoV-1 and related bat coronaviruses that could potentially cause the next pandemic.
The new vaccine, called a pan-coronavirus vaccine, triggers neutralizing antibodies via a nanoparticle. The nanoparticle is composed of the coronavirus part that allows it to bind to the body's cell receptors and is formulated with a chemical booster called an adjuvant. Success in primates is highly relevant to humans.

South-africa , State-of-north-carolina , North-carolina , United-states , United-kingdom , University-of-north-carolina , Brazil , Rachell-spreng , C-todd-demarco , Mahnaz-minai , Surender-khurana , Thomash-oguin