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Many melanoma patients could avoid the risk for toxicity from combination therapies, study suggests

Data from a national clinical trial shows that a striking 89% of patients with desmoplastic melanoma responded to immunotherapy (pembrolizumab) alone, suggesting that many patients could avoid the risk for toxicity from combination therapies and achieve cancer control with this approach to treatment. ....

United States , David Wada , Emily Henderson , Alexandra Ikeguchi , Garyc Doolittle , Elad Sharon , Nikhili Khushalani , Sapnap Patel , Kari Kendra , Katiem Campbell , Antoni Ribas , Joseph Markowitz , Zeynep Eroglu , Arthurg James , Josea Plaza , Toni Roberts , Shay Bellasea , Andres Brohl , Samer Kasbari , Jeffrey Sosman , George Negrea , John Hyngstrom , Michaelc Wu , Ohio State University College Of Medicine , Checkmate Pharmaceuticals , Richardj Solove Research Institute ,

SWOG S1512 trial sees high response rate to p

Close to 90 percent of patients with unresectable (inoperable) desmoplastic melanoma, a rare form of skin cancer, saw their cancer improve after treatment with the immunotherapy drug pembrolizumab in a recent clinical trial. These results from the S1512 trial are being delivered in an oral presentation at the clinical trials plenary session of the 2023 annual meeting of the American Association for Cancer Research (AACR) in Orlando, Florida, on April 16th. ....

Saint Michael , United States , Michaelc Wu , George Negrea , Josea Plaza , Katiem Campbell , Jeffreya Sosman , Antoni Ribas , Garyc Doolittle , Kari Kendra , Andrew Brohl , Nikhil Khushalani , Zeynep Eroglu , Alexandra Ikeguchi , Samer Kasbari , Toni Roberts , Arthurg James , Joseph Markowitz , Shay Bellasea , David Wada , John Hyngstrom , Sapna Patel , Elad Sharon , Cancer Therapy Evaluation Program , National Clinical Trials Network , Md Anderson Cancer Center ,