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Kenneth Saag, MD, explores the clinical significance of a study demonstrating treatment with pegloticase leads to bone remodeling in patients with gout. ....
In osteoporosis, bones become brittle and fragile, putting them at high risk of fractures or breaks. These "fragility fractures" can cause pain, suffering, disability and even death, and patients have increased risks of repeat fractures. ....
The study, funded by the Patient-Centered Outcomes Research Institute, will compare two pathways of post-fracture patient care. The study, funded by the Patient-Centered Outcomes Research Institute, will compare two path. ....
The rheumatology month in review features studies exploring ways to enhance care, an increased risk of adverse COVID-19 outcomes, and pegloticase plus methotrexate co-therapy for gout treatment. ....
At the 12-month mark, response rate in patients with uncontrolled gout was significantly higher in those treated with pegloticase and concomitant methotrexate when compared with placebo. ....