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In a study published in the prestigious scientific journal PNAS, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell.
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For the first time, researchers at Umeå University, Sweden, can now show how the dreaded poliovirus behaves when it takes over an infected cell and tricks the cell into producing new virus particles.
A new multi-institutional study has discovered that the poliovirus tricks infected cells into producing new viral particles by reprogramming an essential cellular process known as autophagy.
Researchers in Umeå have for the first time at the atomic level succeeded in mapping what a virus looks like that causes diarrhea and annually kills about 50,000 children in the world. The discovery may in the long run provide the opportunity for completely new types of treatments for other viral diseases such as COVID-19.