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Vascular Perfusion Solutions Collaborates with Wyss

Study validates Wyss Institute compound for placing mammalian tissues into ‘hiberation’. ....

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Vascular Perfusion Solutions Collaborates with Wyss Institute and U.S. Air Force to Study Compound to Improve Organ Transplant Outcomes

Vascular Perfusion Solutions Collaborates with Wyss Institute and U.S. Air Force to Study Compound to Improve Organ Transplant Outcomes
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Boston University , United States , University Of Massachusetts Medical School , Massachusetts Institute Of Technology , Tufts University , Spaulding Rehabilitation Hospital , Lisa Marie Barocas , Thomas Percival , Mark Muller , Erik Weitzel , Donald Ingber , Mike Super , Us Air , Beth Israel Deaconess Medical Center , Vascular Perfusion Solutions Inc , Farber Cancer Institute , Arts Sciences , Wyss Institute , Defense Advanced Research Projects Agency , Vascular Perfusion Solutions , Institute Biostasis , Biologically Inspired Engineering , Harvard University , Lead Senior Staff Scientist , Founding Director Donald Ingber , Medical Wing ,

Biomaterial vaccines ward off broad range of bacterial infections and septic shock

Biomaterial vaccines ward off broad range of bacterial infections and septic shock
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Biomaterial vaccines ward off broad range of bacterial infections and septic shock

Biomaterial vaccines ward off broad range of bacterial infections and septic shock
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Human organ chips enable COVID-19 drug repurposing

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A Wyss Institute-led collaboration spanning four research labs and hundreds of miles has used the Institute s organ-on-a-chip (Organ Chip) technology to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes COVID-19.
The Organ Chip-based drug testing ecosystem established by the collaboration greatly streamlines the process of evaluating the safety and efficacy of existing drugs for new medical applications, and provides a proof-of-concept for the use of Organ Chips to rapidly repurpose existing drugs for new medical applications, including future pandemics. The research is reported in
Nature Biomedical Engineering.
While many groups around the world have been testing existing drugs for efficacy against COVID-19 using cultured cells, it is well known that cells grown in a dish do not behave like the cells in a living human body, and many drugs that appear effective in lab studies do not work ....

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