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Psychedelic Spurs Growth of Neural Connections Lost in Depression A single dose of psilocybin given to mice prompts an immediate and long-lasting increase in connections between neurons July 6, 2021 Yale University The psychedelic drug psilocybin, a naturally occurring compound found in some mushrooms, has been studied as a potential treatment for depression for years. But exactly how it works in the brain and how long beneficial results might last is still unclear. In a new study, Yale researchers show that a single dose of psilocybin given to mice prompted an immediate and long-lasting increase in connections between neurons. The findings are published July 5 in the journal ....
2 minute read A new study by researchers at Yale University has shown that a single dose of psilocybin given to mice prompted an immediate and long-lasting increase in connections between neurons. Psilocybin is a naturally occurring compound found in magic mushrooms and has been touted as a potential treatment for depression in recent years. However, the mechanics of exactly how psilocybin works in the brain and how long beneficial results might last is still unclear. The research found that the compound increases the density of dendritic spines, small protrusions found on nerve cells that aid in the transmission of information between neurons. Chronic stress and depression are known to reduce the number of these neuronal connections. ....
Psychedelic spurs growth of neural connections lost in depression: Study ANI | Updated: Jul 06, 2021 08:46 IST Washington [US], July 6 (ANI): The psychedelic drug psilocybin, a naturally occurring compound found in some mushrooms, has been studied as a potential treatment for depression for years. However, it is still unclear how it works in the brain and how long beneficial results might last. In a new study, published in the journal Neuron, Yale researchers show that a single dose of psilocybin given to mice prompted an immediate and long-lasting increase in connections between neurons. We not only saw a 10 per cent increase in the number of neuronal connections, but also they were on average about 10 per cent larger, so the connections were stronger as well, said Yale s Alex Kwan, associate professor of psychiatry and of neuroscience and senior author of the paper. ....