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Benefits of Early Belimumab Intervention in SLE, with Karen Costenbader, MD

Karen Costenbader, MD, discusses how early intervention with belimumab in patients with lupus significantly reduces disease flares and prevents irreversible organ damage. ....

Karen Costenbader , Drug Administration , British Isles Lupus Assessment Group , Lupus Program At Brigham , European Congress , Lupus Program , Systemic Lupus Erythematosus Responder Index ,

Patients With Stable Lupus May Be Safely Weaned Off MMF

Rates of significant disease reactivation were similar more than 1 year after randomization for patients assigned to mycophenolate mofetil (MMF) withdrawal or MMF maintenance. ....

United States , Elizaf Chakravarty , Karenh Costenbader , Laurent Chiche , Lupus Program At Brigham , American College Of Rheumatology , Marseille University In , University Of Oklahoma College Medicine , Harvard Medical School , Oklahoma College , Oklahoma City , Medscape Medical , American College , Activity Index , Aix Marseille University , Hopital Europeen De Marseille , Lupus Program , Systemic Lupus Erythematosus Sle Erythaematosus , Drug Withdrawal , Lupus Nephritis , Immunosuppressive Therapy , Immunosuppressive Agents , Immunosuppressive Drugs , Dherence To Medication Issues For Patients , Rug Compliance , Treatment Adherence ,

Global Lupus Experts Recommend Changes to Clinical Trial Outcome Measures to Expedite Development of Therapeutics

/PRNewswire/ Lupus is a complicated and debilitating autoimmune disease, affecting millions of people across the globe. Yet, lupus drug development lags. ....

District Of Columbia , United States , Joan Merrill , Karenh Costenbader , Anca Askanase , Mike Donnelly , Scientific Advisory Council , Lupus Pillars For Health Advancement , Lupus Program At Brigham , Drug Administration , Lupus Foundation Of America , Eric Morand At Monash University , Global Advisory Committee , Addressing Lupus Pillars , Health Advancement , Project Global Advisory Committee , Stakeholder Meeting , Lupus Clinical Trial Outcome Measures , Patient Perspective , Lupus Science , Lupus Foundation , America Medical Scientific Advisory Council Chair , Lupus Program , America Rapid Evaluation , Treatment Response Measure , Eric Morand ,

World Lupus Day 2021: 5 things to know about this mysterious disease

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There is a lot about lupus that is still a conundrum to us, said Dr. Karen H. Costenbader, a professor of medicine at Harvard Medical School and director of the Lupus Program at Brigham and Women s Hospital in Boston.
It s treatable, but it can still be very painful and challenging to overcome, said Costenbader, who is also chair of the Lupus Foundation of America s Medical-Scientific Advisory Council.
May 10 is World Lupus Day, and we recently caught up with Costenbader to learn more about the disease.
This conversation has been edited and condensed for clarity.
CNN: What does it mean that lupus is an autoimmune disease? ....

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5 things to know about the 'conundrum' of lupus

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Lupus is unpredictable, triggering different symptoms in different patients. A chronic illness, it can even attack many different parts of the body.
The condition is an autoimmune disease, which means that a person’s immune system the body system that usually fights infections attacks healthy tissue instead. It can cause inflammation and pain anywhere in a patient’s body.
Because the illness can look different in every patient, it can go undetected and undiagnosed for years.
The Lupus Foundation of America estimates that 1.5 million Americans and at least 5 million people worldwide have some form of lupus. There are four forms in all: systemic lupus erythematosus (SLE), lupus confined to the skin, lupus caused by some prescription drugs and a rare lupus that affects infants of women with the disease. ....

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