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MacroGenics Announces Publication of SOPHIA Trial Results for MARGENZA™ in JAMA Oncology


Published: Jan 25, 2021
(margetuximab-cmkb)
trastuzumab), both with chemotherapy
In the U.S., MARGENZA is approved, in combination with chemotherapy, for the treatment of adult patients with metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens, at least one of which was for metastatic disease
ROCKVILLE, MD, Jan. 25, 2021 (GLOBE NEWSWIRE) MacroGenics, Inc.. (Nasdaq: MGNX), a biopharmaceutical company focused on developing and commercializing innovative monoclonal antibody-based therapeutics for the treatment of cancer, today announced the publication of results from the SOPHIA trial of MARGENZA™ (margetuximab-cmkb) in the
Journal of the American Medical Association (JAMA) Oncology. SOPHIA is a pivotal Phase 3 clinical trial of 536 adult patients with metastatic HER2-positive breast cancer previously treated with two or more anti-HER2 regimens and from one to three lines of therapy for metastatic disease.  In th ....

United States , Jim Karrels , Scott Koenig , Exchange Commission , Macrogenics Inc , Securities Exchange , Journal Of The American Medical Association , Progression Free Survival , American Medical Association , Hazard Ratio , Overall Survival , Important Safety , Breast Oncology , Clinical Trials Education , Response Evaluation Criteria , Solid Tumors , Macrogenic Fc Optimization , Ventricular Dysfunction , Fetal Toxicity , Related Reactions , Prescribing Information , Securities Act , Securities Exchange Act , Senior Vice President , ஒன்றுபட்டது மாநிலங்களில் , ஸ்காட் க்க்நிக் ,

Zai Lab Partner MacroGenics Announces FDA Approval of MARGENZA™ for Patients with Pretreated Metastatic HER2-Positive Breast Cancer


News Category Global Banking & Finance Reviews
Zai Lab Partner MacroGenics Announces FDA Approval of MARGENZA™ for Patients with Pretreated Metastatic HER2-Positive Breast Cancer
MARGENZA (margetuximab-cmkb) is the first HER2-targeted therapy to have improved progression-free survival (PFS) versus Herceptin® (
trastuzumab), both combined with chemotherapy,
in a head-to-head Phase 3 clinical trial
MARGENZA is approved, in combination with chemotherapy, for the treatment of adult patients with metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens, at least one of which was for metastatic disease
Product launch in U.S. anticipated in March 2021
SHANGHAI and SAN FRANCISCO, Dec. 16, 2020 Zai Lab Limited’s (NASDAQ: ZLAB; HKEX: 9688) partner MacroGenics, Inc. (Nasdaq: MGNX), a biopharmaceutical company focused on developing and commercializing innovative monoclonal-antibody-based therapeutics for the treatment of ....

D Burns Mcclellan , Pete Rahmer Mike Zanoni , Ryo Imai Robert Flamm , Zai Lab Billy Cho , Macrogenics Inc , Zai Lab In Greater China , Zai Lab , Drug Administration , Zai Lab Limited , Chief Executive Officer , Overall Survival , Response Evaluation Criteria , Solid Tumors , Macrogenic Fc Optimization , Prescribing Information , Lab Billy Cho , Ryo Imai , Robert Flamm , Pete Rahmer , Mike Zanoni Endurance Advisors , ட தீக்காயங்கள் ம்க்க்லெல்யாந் , ஜா ஆய்வகம் பில்லி சோ , ஜா ஆய்வகம் இல் அதிகமானது சீனா , ஜா ஆய்வகம் , ஜா ஆய்வகம் வரையறுக்கப்பட்டவை , தலைமை நிர்வாகி அதிகாரி ,