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More new SARS-CoV-2 variants are highly likely In a recent report posted to the bioRxiv* preprint server, researchers from the United Kingdom and Uganda reveal unique protein features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relative to other representatives of Sarbecoviruses. The causative agent of the coronavirus disease 2019 (COVID-19), SARS-CoV-2, belongs to the Betacoronavirus genus and Coronaviridae family, which is a group of enveloped, single-stranded RNA viruses. Other representatives of Sarbecoviruses include SARS-CoV (which was the coronavirus that led to ...

Abstract Central nervous system (CNS) infection is a serious neurologic condition, although the etiology remains unknown in >50% of patients. We used metagenomic next-generation sequencing to detect viruses in 204 cerebrospinal fluid (CSF) samples from patients with acute CNS infection who were enrolled from Vietnam hospitals during 2012–2016. We detected 8 viral species in 107/204 (52.4%) of CSF samples. After virus-specific PCR confirmation, the detection rate was lowered to 30/204 (14.7%). Enteroviruses were the most common viruses detected (n = 23), followed by hepatitis B virus (3), HI...