Pain Receptors Help to Generate Brown Fat Cells
Vascular smooth muscle-derived Trpv1+ progenitors have found to be a source of cold-induced 'brown fat'
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Vascular smooth muscle-derived Trpv1+ progenitors have found to be a source of cold-induced 'brown fat'
E-Mail BOSTON - (April 12, 2021) - A new source of energy expending brown fat cells has been uncovered by researchers at the Joslin Diabetes Center, which they say points towards potential new therapeutic options for obesity. According to the new report, published today by Nature Metabolism, the key lies in the expression of a receptor called Trpv1 (temperature-sensitive ion channel transient receptor potential cation subfamily V member 1) -- a protein known to sense noxious stimuli, including pain and temperature. Specifically, the authors point to smooth muscle cells expressing the Trpv1...