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AI foundation model for eye care to supercharge global efforts to prevent blindness

AI foundation model for eye care to supercharge global efforts to prevent blindness
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

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World-First AI Foundation Model for Eye Care to Accelerate Global Efforts in Preventing Blindness

RETFound, one of the first AI foundation models in healthcare, and the first in ophthalmology, was developed using millions of eye scans from the NHS. The research team are making the system open-source: freely available to use by any institution wor ....

United Kingdom , City Of , Yukun Zhou , Alastair Denniston , Pearse Keane , Google Deepmind , Institute Of Ophthalmology , Centre For Medical Image Computing , Birmingham Biomedical Research Centres , Professor Pearse Keane , Moorfields Eye Hospital , Professor Alastair Denniston , Medical Image Computing , Biomedical Engineering , Moorfields Eye , Biomedical Research Centres , Computer Science ,

New AI System Helps Prevent Blindness Across the Globe

At University College London (UCL) and Moorfields Eye Hospital, scientists have come up with an artificial intelligence (AI) system that could not just determine sight-threatening eye diseases but also forecast general health, such as stroke, heart attacks, and Parkinson’s disease. ....

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World-first AI foundation model for eye care to supercharge global efforts to prevent blindness

World-first AI foundation model for eye care to supercharge global efforts to prevent blindness
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

United Kingdom , City Of , Google Deepmind , Pearse Keane , Yukun Zhou , Alastair Denniston , Institute Of Ophthalmology , Moorfields Eye Hospital , Professor Pearse Keane , Professor Alastair Denniston , Medical Image Computing , Biomedical Engineering , Moorfields Eye ,

Specialized astrocytes mediate glutamatergic gliotransmission in the CNS

Multimodal astrocyte–neuron communications govern brain circuitry assembly and function1. For example, through rapid glutamate release, astrocytes can control excitability, plasticity and synchronous activity2,3 of synaptic networks, while also contributing to their dysregulation in neuropsychiatric conditions4–7. For astrocytes to communicate through fast focal glutamate release, they should possess an apparatus for Ca2+-dependent exocytosis similar to neurons8–10. However, the existence of this mechanism has been questioned11–13 owing to inconsistent data14–17 and a lack of direct supporting evidence. Here we revisited the astrocyte glutamate exocytosis hypothesis by considering the emerging molecular heterogeneity of astrocytes18–21 and using molecular, bioinformatic and imaging approaches, together with cell-specific genetic tools that interfere with glutamate exocytosis in vivo. By analysing existing single-cell RNA-sequencing databases and our ....

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