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fatal dose. >> it was dr. murray's repeated incompetent and unskilled acts that led to mr. jackson's death on june 25, 2009. >> michael jackson swallowed up to eight pills on his own without telling his doctor, without permission from his doctor. and when dr. murray gave him the 25 milligrams and dr. murray left the room, michael jackson self-administered a dose, an additional dose of propofol. and it killed him. >> watching the beginning of the trial, you realize this whole thing may boil down to propofol and how michael jackson and conrad murray were using it. now when i first hear...

of opening statements that will be live when things get going. well, another high-profile trial is winding down. attorneys for amanda knox will make their final arguments. they are hoping to overturn her murder conviction. knox is expected to speak as well. prosecutors claim that knox slit her roommate's throat during wild sex. libyan fighters say that they have seized the port of sirte today. moammar gadhafi controls most of the city. this is one of the areas not under the control of libya's new leadership. washington dodges a government shutdown. lawmakers have a deal in hand...

there, or are you alone? >> reporter: i am alone except for the crew and some other reporters. i had to look around. we're sort of in a bubble. you know how that is, but, where do we start, ali? oh my gosh. there is so much to talk about in this case. when you talk about propofol. we didn't know anything about propofol before michael jackson. some people get it when you go into procedures but you didn't know the name of it. as you said, opening statements, starting about 8:45 local time, which is 11:45 eastern. that's when the judge will come in, give the jury instructions, about 15 ...

>> ted rowlands was inside the courtroom when that audio was played. ted, it was stunning to hear. i can't imagine what the reaction was like inside the courtroom where michael jacks jackson's family was attending. >> reporter: to be honest, drew, i was not inside the courtroom during that audio, but i think anybody who heard it was shocked. and the prosecutors used it for one reason, to show that dr. conrad murray knew what he was doing to michael jackson, knew the drugs he was administering to michael jackson had this type of effect. they got that recording from murray's own cell p...

Breathing for him. >> for one thing worth pointing out is this is a hospital that uses this medication thousands and thousands of times a year. but they use it in non-hospital settings like outpatient clinics. they've never heard of it being used in a home. anderson, back to you. >> unbelievable how quickly it stops a patient's breathing even under the right settings. the patient you saw going under is doing fine now. he woke up shortly after the surgery without any complications. still ahead tonight, dramatic video, the freak killer wave that swept spectators out to sea off maine's coast. f...