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Unexpected Protective Properties of Pain - Neuroscience News

Pain neurons engage in direct cross-talk with goblet cells, or mucus-containing cells within the gut. During states of inflammation, pain cells stimulate goblet cells to release more mucus. Findings suggest the nervous system plays a key role in gut barrier maintenance and triggers protective mechanisms during periods of inflammation. ....

Malin Johansson , Amanda Jacobson , Ddaping Yang , Joseph Sifakis , Praju Vikas Anekal , Nicole Lee , Samantha Choi , Michael Anderson , Bana Jabri , Alexandra Sontheimer Phelps , Deepika Sharma , Youlian Zhou , Ekaterina Pesheva , Dennis Kasper , Jun Huh , Dylan Neel , Jay Thiagarajah , Meng Wu , Isaac Chiu , Samantha Riesenfeld , Tiandi Yang , Kimberly Meerschaert , Rachel Rucker , Liwen Deng , Chiu Lab Harvard Medical School , National Institutes Of Health ,