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Pioneering COVID-19 vaccines could lead to cures The RNA jabs developed to fight coronavirus also have potential to treat other maladies including cancer and rare genetic diseases diagnosed in the womb. Long before the coronavirus, scientists envisioned using RNA to treat a variety of human diseases, including cystic fibrosis and sickle-cell anaemia.  Getty Share A few weeks ago, a group of scientists reported that they had injected mice with genetic instructions in the form of RNA, prompting the animals’ cells to produce customised proteins. That may seem like no big deal, given millions ...

RNA worked for COVID-19 vaccines. Could it be used to treat cancer and rare childhood diseases? Tom Avril, The Philadelphia Inquirer A few weeks ago, a group of Philadelphia scientists reported that they had injected mice with genetic instructions in the form of RNA, prompting the animals’ cells to produce customized proteins. If that seems like no big deal at this point, now that millions have undergone a similar process in being vaccinated against COVID-19, guess again. These injections were not vaccines, and the mice in question were fetuses, so the RNA had to be administ...

/PRNewswire/ -- Researchers at Children's Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have...

Credit: Children's Hospital of Philadelphia Philadelphia, January 13, 2021--Researchers at Children's Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy. The proof-of-concept study, published today in Science Advances, engineered and screened a number of lipid nanoparticle formulations for targeting mouse fetal organs and has laid the groundwork for testing potential therapies to treat genetic diseases before birth. "This is an im...