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Introduction To The New ASTM E3418 Standard Practice For Calculating Scientifically Justifiable Limits Of Residues For Cleaning Of Pharmaceutical And Medical Device Manufacturing Equipment And For Medical Devices

Introduction To The New ASTM E3418 Standard Practice For Calculating Scientifically Justifiable Limits Of Residues For Cleaning Of Pharmaceutical And Medical Device Manufacturing Equipment And For Medical Devices
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United States , Reto Luginbuehl , Michel Crevoisier , Alfredo Canhoto , Randall Thoma , Thomas Altmann , Sarra Boujelben , Ralph Basile , Christophe Gamblin , Mariann Neverovitch , Ajay Kumar Raghuwanshi , Boopathy Dhanapal , Mallory Degennaro , Davidg Dolan , Siegfried Schmitt , Spiro Megremis , Andreas Flueckiger , Ioanna Maria Gerostathi , Jove Graham , Mohammad Ovais , Jayen Diyora , Ester Lovsin Barle , Stephen Spiegelberg , Delane Dale , Ioana Gheorghiev , Igor Gorsky ,

Calculating Process Capability Of Cleaning Processes Analysis Of Total Organic Carbon (TOC) Data

Calculating Process Capability Of Cleaning Processes Analysis Of Total Organic Carbon (TOC) Data
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Ester Lovsin Barle , Miquel Romero Obon , Andreas Flueckiger , Davidg Dolan , Gabriela Cruz , Ioana Gheorghiev , Igor Gorsky , Basundhara Sthapit , Robert Kowal , Mallory Degennaro , Laurence Oleary , James Bergum , Kailash Rathi , Andrew Walsh , Michel Crevoisier , Kenneth Farrugia , Sarra Boujelben , Thomas Altmann , Mariann Neverovitch , Alfredo Canhoto , Osamu Shirokizawa , Pernille Damkjaer , David Dolan , Kelly Waldron , Christophe Gamblin , Ajay Kumar Raghuwanshi ,

Introduction To ASTM E3263-20 Standard Practice For Qualification Of Visual Inspection Of Pharmaceutical Manufacturing Equipment And Medical Devices For Residues


Introduction To ASTM E3263-20:
By Andrew Walsh, Ralph Basile, Ovais Mohammad, Stéphane Cousin, Mariann Neverovitch, and Osamu Shirokizawa
Part of the
series
Visual inspection has been widely used for many years by the pharmaceutical, biologics, and medical device industries after cleaning to release manufacturing equipment and devices. However, visual inspection has never been demonstrated to be an effective, reliable, or safe method to use for these inspections. Recently, the European Medicines Agency (EMA) issued a Q&A
1 to its guideline on determining health-based exposure limits (HBELs) that describes what criteria have to be met for visual inspection to be acceptable to the EMA for release of manufacturing equipment. Some form of guidance or a standard has been needed to guide these industries on how to meet these criteria and demonstrate that operators/QA inspectors are capable and qualified to accurately assess the absence or presence of residues on m ....

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