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Automated IR-Spectroscopy for Analysis of Protein Biopharmaceuticals


Automated IR-Spectroscopy for Analysis of Protein Biopharmaceuticals
May 5, 2021
Time: 8:00 am PT, 11:00 am ET, 17:00 CET
Higher-order structure is an important critical quality attribute that correlates structure-function characteristics with safety and efficacy for protein biotherapeutics. Infrared (IR) spectroscopy has long been recognized as a powerful biophysical tool for determining protein secondary structure and monitoring dynamic structural changes. Structural analysis helps establish process and product knowledge, inform the impact of upstream (cell culture) and downstream (purification) process conditions, identify stable formulations, monitor product stability, and assess product comparability when process improvements are implemented. Within the market of biosimilars, the characterization of secondary structure is paramount in determining similarity with established, commercially available molecules.   ....

Lucy Liu , Broadcast Date , Microfluidic Modulation Spectroscopy , Microfluidic Modulation , Fourier Transform , லூசி லியூ , ஒளிபரப்பு தேதி ,