Re-activating a compromised immune system to fight sepsis
Failure of the immune system during blood poisoning (sepsis) can be reversed by a specific sugar.
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Failure of the immune system during blood poisoning (sepsis) can be reversed by a specific sugar.
<p><strong>Bacillus Calmette-Guérin (BCG) is one of the world’s oldest and most widely used vaccines. It was developed in the early 20<sup>th</sup> century to provide protection from tuberculosis. Surprisingly, this vaccine protects not only against tuberculosis but also reduces the risk for various other infections, through a mechanism called trained immunity. A new study led by Christoph Bock and Mihai Netea found that epigenetic cell states predict whether or not an individual profits from the “wake-up call” to the innate immu...
What if a vaccine, given to patients just before or after arriving at the hospital, could protect them against lethal superbugs that lurk in healthcare settings?
Agnolo di Tura was a sometime shoemaker and tax collector with a yen for keeping a journal.
We are the descendants of the survivors, and our genomes show it