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Moderna Says Covid Vaccine Highly Effective In Adolescents

Moderna said it will seek US regulators' approval in June (File)
Washington:
US biotech firm Moderna said Tuesday that trials had shown its Covid-19 vaccine is "highly effective" in adolescents aged 12-17 and the company would seek regulators' approval in June.
"We are encouraged that mRNA-1273 was highly effective at preventing Covid-19 in adolescents," CEO Stephane Bancel said in a statement.
"We will submit these results to the US FDA and regulators globally in early June and request authorization."
If greenlit, as expected, it would be the second Covid vaccine authorized for use in US adolescents after Pfizer's, which began rolling out this month for 12-to-15-year-olds.

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Moderna vaccine: Moderna Covid vaccine efficacy falls slightly to 90% in US trial

Synopsis
A company press release did not indicate why efficacy has fallen, but one reason might be the emergence of new variants of concern which are not as susceptible to antibodies evoked to the vaccine.
Agencies
Moderna is working on two variant-specific boosters, and said mice studies showed they elicited an increased immune response. The results of these studies have been posted online in a scientific paper that is now awaiting peer review.
US biotech company Moderna announced Covid vaccine is 90 percent effective against all forms of the disease and 95 percent effective against severe disease.
The new results come from its ongoing Phase 3 clinical trial involving more 30,000 people across the United States, and the headline efficacy figure is a slight decrease from an earlier figure of 94.1 percent published in the New England Journal of Medicine in December.

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