PDX Mouse Models Match Genetics of Human Tumors
February 2, 2021, by NCI Staff PDX mice largely retain the genetics of the human tumors from which they were initially created, a new study shows. Credit: Adapted from image provided courtesy of Jackson Laboratory. Mouse models are among the most valuable tools in cancer research. Researchers use them for many types of studies, from identifying possible new cancer treatments to finding new clues about cancer biology. But mice aren’t humans. So developing mouse models that provide meaningful research results—namely, by ensuring they replicate how cancer behaves in humans as closely...
Source: cancer.gov