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Large genome-wide association study on nonalcoholic fatty liver disease

Scientists at deCODE genetics in Iceland have discovered rare, protective loss-of-function variants that point to potential drug targets for nonalcoholic fatty liver disease (NAFLD). ....

United States , United Kingdom , Emily Henderson , Genomics Industry Focus , Fatty Liver , Liver Disease ,

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients. ....

Aimee Molineux , Neha Mathur , Neha Mathuroct , Drug Administration , Genomics Industry Focus , Federal Drug Administration , Coronavirus Disease Covid 19 , Clinical Trial , Immune Response , Retinoic Acid , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Strong facial similarity in people is linked with shared genetic variants

A collection of photos of genetically unrelated lookalikes, along with DNA analysis, revealed that strong facial similarity is associated with shared genetic variants. ....

Comunidad Autonoma De Cataluna , Manel Esteller Manelesteller , Emily Henderson , Cellex Foundation , Josep Carreras Leukaemia Research Institute , Senior Author , World Wide Web ,

Multiomics identifies genomic risk factors for COVID-19

In a recent Cell Systems study, researchers utilized the RefMap machine learning algorithm to correlate known genomic variations for severe COVID-19 obtained from large-scale genome-wide association studies (GWAS) with single-cell multiome profiling of human lungs. ....

Alpha Tauri , Cell Systems , Coronavirus Disease Covid 19 , Immune Response , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,