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Blogs | | Chimeric antigen receptor T-cell therapy targeting CD19 is highly effective for inducing remission among patients with relapsed or refractory B-cell acute lymphoblastic leukemia.Despite that, 50% of patients relapse after CAR-T therapy, and curative options for patients who relapse after CD19 CAR-T are limited, with no standard approach to cure.
The Food and Drug Administration on December 15 approved the first-ever drug to be used for the prevention of acute graft versus host disease (aGVHD) in adult and pediatric patients, opening the door for safer bone marrow and blood stem cell transplants in patients who do not have a perfectly matched graft donor.
The Food and Drug Administration on December 15 approved the first-ever drug to be used for the prevention of acute graft versus host disease (aGVHD
email article A widely used arthritis drug reduced the rate of acute graft-versus-host disease (GVHD) in both HLA-matched and -mismatched allogeneic stem-cell transplants, a randomized study showed. The incidence of grade 3/4 acute GVHD after matched transplants decreased from 14.8% with standard prophylaxis to 6.8% with the addition of abatacept (Orencia). In a small group of patients who had 7/8-HLA-mismatched transplants, grade 3/4 acute GVHD at day 100 declined significantly from 30.2% with standard prophylaxis to 2.3% with add-on abatacept ( P 0.001). Treatment with abatacept was n...
Andy Warhol Foundation grant to support book completion Sergio Delgado Moya, associate professor of Spanish and Portuguese, has been awarded one of the Andy Warhol Foundation’s Arts Writer Grants. Projects supported by the program address both general and specialized art audiences, from scholarly studies to critical reviews and magazine features. Moya will receive $50,000 to complete his book “An Archive of Violence: The Obscene Visuality of Sensationalism.” The book makes a case for sensationalism as a specific kind of violence that falls on marginalized populations who are marked b...