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Advancing the Treatment Landscape for Patients With Myeloproliferative Neoplasms

This group of cancers remains a challenge to diagnose, can be rapidly progressive, and requires complex treatment and follow-up care, research suggests. ....

United States , National Oncology Conference , World Health Organization , Association Of Community Cancer Centers , Community Cancer Centers , Oncology Conference , Rare Disease , Myeloproliferative Neoplasms , Polycythemia Vera , Essential Thrombocythemia ,

Comorbidity Index Predicts Vulnerability of Patients With Myelofibrosis

The American Journal of Managed Care provides insights into the latest news and research in managed care across multimedia platforms. ....

Dynamic International Prognostic Scoring System , Myelodysplastic Syndrome , Specific Comorbidity Index , Cantonal Hospital ,

Australian-developed blood cancer treatment approved by FDA

The FDA has approved GSK's cancer drug Ojjaara (momelotinib) for the treatment of intermediate or high-risk myelofibrosis in adults with anaemia. ....

Nina Mojas , Nemes Laszlo , Andrew Wilks , Senior Vice President , Oncology Global Product Strategy , Professor Andrew , Sierra Oncology , One Marrow Blood Cancer ,

FDA grants broad label for GSK's momelotinib in myelofibrosis with anemia

Five years after Gilead Sciences Inc. gave up on momelotinib in the wake of two phase III failures in myelofibrosis, the JAK1/2 and ACVR1 inhibitor has found its way to the market in the hands of GSK plc. Branded Ojjaara, the drug gained U.S. FDA approval for use in intermediate- or high-risk myelofibrosis patients with anemia regardless of prior administration with JAK inhibitors such as Jakafi (ruxolitinib, Incyte Corp.). The approval came a day before the Sept. 16 PDUFA date, which had been extended by three months in June to allow the agency to review recently submitted data. A rare blood cancer characterized by dysregulated JAK-signal transducer and resulting in splenomegaly and progressive anemia, myelofibrosis affects roughly 25,000 people in the U.S. ....

Gilead Sciences Inc , Incyte Corp , Gilead Sciences , Jak1 2 , Gsk Plc , Jak Inhibitors , Incyte Corp ,

US FDA approves GSK treatment for myelofibrosis

GSK announced on Monday that the US Food and Drug Administration (FDA) has granted approval for ‘Ojjaara’, or momelotinib, as a treatment for adults suffering from intermediate or high-risk myelofibrosis with anaemia, including cases of primary myelofibrosis or secondary myelofibrosis. ....

Nina Mojas , Category All , Category Market Report , Category Company News , Category News And Announcements , Category Market Pulse , Category Headline News , Category Sectorial Health Technology ,