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Myelofibrosis: Potential Impact of Pacritinib on Anemia

Experts continue their conversation on pacritinib in myelofibrosis by reviewing its potential impact on anemia and ACVR1. ....

Potential Impact , Mf Cancer , Primary Myelofibrosis , Mechanism Of Action , Acvr1 Inhibition , Irak Inhibitors , Irak Inhibition ,

BMS-986158–Based Combos May Provide Another Viable Treatment Approach in Myelofibrosis

Haifa Kathrin Al-Ali, MD, provides background on the phase 1/2 study of BMS-986158, presents initial efficacy and safety data from the study, and discusses her hope that novel combination regimens like these could achieve the challenging goal of disease modification in myelofibrosis in the future. ....

Haifa Kathrin Al Ali , University Hospital Of Halle Saale , Krukenberg Cancer Center , Translational Oncology , University Hospital , Bms 986158 , Bet Inhibitor , Phase 1 2 Ca011 023 Trial Nct04817007 ,

Evolving Treatment Armamentarium for Myelofibrosis

Key opinion leaders provide a broad perspective on the current treatment armamentarium available to patients diagnosed with myelofibrosis. ....

Treatment Armamentarium , Mf Cancer , Primary Myelofibrosis , Jak Inhibitors , Jak Inhibition , Jak Stat Pathway , Jak Stat , Allogeneic Transplant , Allogeneic Stem Cell Transplant ,