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New preclinical data on the antifibrotic effects of tasquinimod in myelofibrosis to be presented at EHA 2023

Lund, May 11 2023 – Active Biotech announces today that new data on the mechanisms by which tasquinimod ameliorates bone marrow fibrosis in a murine model of myelofibrosis will be presented in. | May 11, 2023 ....

Active Biotech Ab Publ Stock Exchange , Press Release , Resented Acti Se0001137985 ,

Dr Jain on Baseline Differences Across Different Donor Types in Myelofibrosis

Tania Jain, MBBS, discusses notable differences in baseline characteristics and donor sequencing, according to a retrospective study of patient outcomes following blood or marrow transplant in 4 common donor types of myelofibrosis. ....

Tania Jain , Sidney Kimmel Comprehensive Cancer Center , Hematological Malignancies , Johns Hopkins Medicine , Myeloproliferative Neoplasms , Onclive Tv ,

Researchers Develop Prognostic Model for Survival in Patients With MF Undergoing Allo-HCT

In addition to current available risk scores, the new system can help counsel patients with myelofibrosis (MF) undergoing allogeneic hematopoietic stem cell transplantation (allo-HCT), authors wrote. ....

United States , Marrow Transplant Research , United States The Center , Dynamic International Prognostic , European Bone Marrow Transplant , Allo Hct , Prognostic Model , Transplant Related Mortality ,

MANIFEST-2 Study of Pelabresib Plus Ruxolitinib Completes Enrollment in Myelofibrosis

Enrollment to the phase 3 MANIFEST-2 trial, which is examining the safety and efficacy of pelabresib plus ruxolitinib vs ruxolitinib alone in patients with JAK inhibitor–naïve myelofibrosis, has completed and topline findings are anticipated by the end of 2023. ....

New York , United States , John Mascarenhas , Dynamic International Prognostic Scoring System , Blood Cancers , Myeloid Disorders , Mount Sinai , Myeloproliferative Neoplasms , Phase 3 Manifest 2 Trial ,