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Findings from MOST Trial Presented at ISC24: Blood thinners added to clot-busting medication did not improve stroke outcomes

Researchers presenting preliminary late-breaking science presented on the first day of the American Stroke Association’s International Stroke Conference 2024 reported findings from the highly-anticipated MOST (Multi-Arm Optimization of Stroke Thrombolysis) trial. The results showed that giving blood thinners in addition to clot-busting medications to people with ischemic strokes (clot-caused strokes) did not improve their outcomes 90 days later. ....

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Combining clot busters and blood thinners shows no advantage for people with ischemic strokes

Giving blood thinners in addition to clot-busting medications to people with ischemic strokes (clot-caused strokes) did not improve their outcomes 90 days later, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024. ....

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MOST: Eptifibatide, Argatroban Don't Improve on IV Thrombolysis Alone

It’s possible that other classes of antithrombotics may be worth adding to improve reperfusion, but that’s conjecture right now. ....

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ARCADIA: Apixaban Not Superior to Aspirin in Reducing Recurrent Stroke Risk

Anticoagulation and antiplatelet therapy show no significant difference in recurrent stroke risk among patients with cryptogenic stroke and evidence of atrial cardiopathy. ....

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Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy

This clinical trial compares the effectiveness of anticoagulation vs antiplatelet therapy for secondary stroke prevention in patients with cryptogenic stroke an ....

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