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ICIs Improve pCR Rates in Early ER+/HER2– Breast Cancer

Two randomized trials highlighted the benefit of adding immune checkpoint inhibitors to neoadjuvant chemotherapy in patients with early high-risk estrogen receptor–positive, HER2-negative breast cancer. ....

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Dr Tina Cascone Details Impact of Nivolumab Chemo-Immunotherapy on NSCLC

Tina Cascone, MD, PhD, of the University of Texas MD Anderson Cancer Center, discusses the impact of the CheckMate 77T study on the treatment approach for non–small cell lung cancer (NSCLC). ....

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No Benefit to Adding ICI to Chemo in TNBC

The Michelangelo trial revealed that adding atezolizumab to nab-paclitaxel and carboplatin did not improve 5-year event-free survival in patients with triple-negative breast cancer. ....

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Perioperative Nivolumab Improves EFS in Resectable NSCLC

Interim findings from CheckMate 77T show an overall improvement in event-free survival with perioperative nivolumab vs neoadjuvant nivolumab plus chemotherapy only. ....

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Can Some Patients With Esophageal Cancer Avoid Surgery?

About one third of patients with esophageal cancer who have a compete response to neoadjuvant chemoradiotherapy may be able to avoid surgery. However, one expert questioned the study design. ....

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