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Concomitant Use of SSRIs and Oral Anticoagulants Increases Major Bleeding Risk

SSRIs increase major bleeding risk by about 33% for patients with atrial fibrillation who are also using oral anticoagulants.

United kingdomNoacs doacsInternational classification of diseasesUnited kingdom clinical practice research datalinkInternational classificationTenth revision

Concomitant Use of SSRIs and Oral Anticoagulants Increases Major Bleeding Risk

SSRIs increase major bleeding risk by about 33% for patients with atrial fibrillation who are also using oral anticoagulants.

United kingdomNoacs doacsUnited kingdom clinical practice research datalinkInternational classification of diseasesInternational classificationTenth revision

Concomitant Use of SSRIs and Oral Anticoagulants Increases Major Bleeding Risk

SSRIs increase major bleeding risk by about 33% for patients with atrial fibrillation who are also using oral anticoagulants.

United kingdomNoacs doacsUnited kingdom clinical practice research datalinkInternational classification of diseasesInternational classificationTenth revision

Concomitant Use of SSRIs and Oral Anticoagulants Increases Major Bleeding Risk

SSRIs increase major bleeding risk by about 33% for patients with atrial fibrillation who are also using oral anticoagulants.

United kingdomNoacs doacsUnited kingdom clinical practice research datalinkInternational classification of diseasesInternational classificationTenth revision

Asundexian Phase 3 AF Study Halted for Lack of Efficacy

The phase 3 OCEANIC-AF trial of the factor XI inhibitor asundexian (Bayer) has been stopped early owing to inferior efficacy vs apixaban in preventing stroke and systemic embolism in patients with AF.

United statesNorth carolinaNoacs doacsChristian rommelManesh patelGlobal head of researchDuke clinical research instituteMedscape cardiologyGlobal headChristian ruffAtrial fibrillationF atrial fibrillationAnticoagulation therapyErebrovascular accidentVa cerebrovascular accidentAnti thrombotics

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