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UK Approves CRISPR-Based Gene Therapy For Inherited Blood Disorders

Gene therapy takes a giant leap forward as Exa-cel becomes the world’s first CRISPR/Cas9 gene-edited therapy approved to treat sickle cell disease and thalassemia. ....

United Kingdom , United States , Emmanuelle Charpentier , Jennifer Doudna , Novel Therapy , Inherited Blood , Regularly Interspaced Short Palindromic Repeats , Crispr Cas9 , Gene Therapy , Sickle Cell Disease , Nobel Prize ,

Interpreting Results From RAMP 201: Avutometinib +/- Defactinib in Recurrent LGSOC

Expert oncologist David M. O’Malley, MD, reviews data from the RAMP 201 study utilizing avutometinib +/- defactinib in patients with recurrent low grade serous ovarian cancer and considers how this combination approach may impact the treatment landscape. ....

Expert Perspectives , Emerging Therapies , Low Grade Serous Ovarian Cancer , Ovarian Cancer , Ramp 201 , Novel Therapy , Combination Therapy , Recist Response , Efficacy Data , Efficacy Outcomes , Ramp 301 , Multidisciplinary Care , Healthcare Team , Clinical Trials , Clinical Trial Access , Access To Clinical Trials ,

COMING SOON: Precision Oncology: Molecular Genotyping and Optimal Treatment of Metastatic Nonsquamous NSCLC

Expert oncologist Charu Aggarwal, MD, MPH, shares her excitement for an upcoming program centered on molecular genotyping and its role in the setting of metastatic nonsquamous non–small cell lung cancer management. ....

Precision Oncology , Molecular Genotyping , Optimal Treatment , Metastatic Nonsquamous , Non Small Cell Lung Cancer , Lung Cancer , Molecular Testing , Biomarker Testing , Targeted Therapy , Novel Therapy ,