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New view of species interactions offers clues to preserve threatened ecosystems


Analysis reveals forest connections that underscore diversity s role in ecosystem health
A blue magpie in Sri Lanka s Sinharaja Forest Reserve, a site that was part of the study.
May 27, 2021
As the health of ecosystems in regions around the globe declines due to a variety of rising threats, scientists continue to seek clues to help prevent future collapse.
A new analysis by scientists around the world, led by a researcher at the University of California, San Diego, is furthering science s understanding of species interactions and how diversity contributes to the preservation of ecosystem health.
A coalition of 49 researchers examined data describing tree species in forests located across a broad range of countries, ecosystems and latitudes. Information about the 16 forest diversity plots in Panama, China, Sri Lanka, Puerto Rico and other locations many in remote, inaccessible areas was collected by hundreds of scientists over decades. ....

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Engineered organism could diagnose Crohn's disease flareups


Bioengineers create pH-sensing gut bacteria to diagnose inflammatory bowel disease
Researchers engineered a strain of the gut bacteria E. coli to detect gastrointestinal acidosis.
May 25, 2021
In an important step toward the clinical application of synthetic biology, Rice University researchers have engineered a bacterium with the capability of diagnosing a human disease.
An engineered strain of the gut bacteria
E. coli senses pH and glows when it encounters acidosis, an acidic condition that often occurs during flareups of inflammatory bowel diseases like colitis, ileitis and Crohn s disease. The pH-sensing circuit was discovered by Rice researcher Kathryn Brink.
Researchers at the University of Colorado then used the Rice-created organism in a mouse model of Crohn s disease to show that acidosis activates a signature set of genes. The corresponding genetic signature in humans has been observed during active inflammation in Crohn s disease patients. The U ....

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