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Hawai‘i Community Foundation today announced a monumental donation of $4 million from Oak Foundation to its Maui Strong Fund. This contribution is the largest single gift the fund has received from a philanthropic entity.
The CONSORT (CONsolidated Standards Of Reporting Trials) 2010 statement is the standard guideline for reporting completed randomised trials. The CONSORT Dose-finding Extension (DEFINE) extends the guidance (with 21 new items and 19 modified items) to early phase dose-finding trials with interim dose escalation or de-escalation strategies. Such trials generally focus on safety, tolerability, activity, and recommending dosing and scheduling regimens for further clinical development. These trials are often inadequately reported, hampering their informativeness and making evidence informed decisio...
SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 provides guidance for clinical trial protocol writing. However, neither the original guidance nor its extensions adequately cover the features of early phase dose-finding trials. The SPIRIT Dose-finding Extension (DEFINE) statement is a new guideline that provides recommendations for essential items that should be provided in the protocols of these trials. It details extensions to the SPIRIT 2013 guidance, incorporating 17 new items and modifying 15 existing items. The purpose of this guideline is to promote trans...
The Maui Strong Fund receives a $4 million dollar donation from the Oak Foundation, the Hawaii Community Foundation announced.
Claims Apple is being taken down by the Democratic party illuminati The Tame Apple Press has been rushing to defend its favourite company from a...