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Inflation concerns are driving markets and we are watching five data points for signs of improvement.

Able to escape the effects of the immune -- of the vaccine? >> reporter: while it will take weeks to have any definitive answers, south africa -- the country that first identified this variant -- is offering clues. >> it has mutations that are similar to the delta variant. so, we are expecting it to transmit faster and based on the early evidence we see in south africa, it's certainly transmitting faster than the delta variant. >> reporter: already confirmed in at least 15 countries, it's clear, omicron is making its way across borders. >> it's almost definitely here already. >> reporter: tryi...

Vaccines. federal health officials are bracing for the first official omicron cases in the u.s. so they say there are likely far more infections across the globe than currently reported. dr. anthony fauci is going to join us to answer all of our questions on this new variant. first as amara walker reports, the rush to get ahead of this new variant is happening in the united states before experts know for sure if it's here or how widespread or how severe. >> reporter: omicron is a stark reminder this pandemic is not yet over. >> it's just got more of things that we don't like the look of. but...

possible iranian nuclear weapon. i'm wolf blitzer and you're in "the situation room." he's made a fortune stoking conservative passions while poking and proding at liberals and rush limbaugh has seen his share of controversies but this time it's different. the outrage he sparked when he called a conception advocate a slut and a prostitute has snowballed, one after the other and major advertisers are pulling their ads from his radio show and there's no sign that the uproar is dying down. lisa sylvester is working the story. what's the latest on rush limbaugh and all his advertisers?...