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Dr Ghassan Abou-Alfa Explains STRIDE Regimen's Priming Dose of Tremelimumab

In his explanation of the tremelimumab priming dose, Ghassan Abou-Alfa, MD, medical oncologist at Memorial Sloan Kettering Cancer Center, also reviews and analogizes checkpoint inhibitors as a whole. ....

Sloan Kettering , Craig Thompson , Jim Allison , Memorial Sloan Kettering Cancer Center , Ghassan Abou Alfa , Nobel Prize , Memorial Sloan Kettering , Checkpoint Inhibitors ,

Niraparib Maintenance Therapy Improves PFS by 55% in Advanced Ovarian Cancer

Results of the phase 3 PRIME study showed that treatment with niraparib with an individualized starting dose significantly extended progression-free survival (PFS) and reduced the risk of disease progression or death by 55% compared with placebo. ....

Ovarian Cancer ,

Atezolizumab added to cabozantinib does not improve clinical outcomes in patients with metastatic renal cell carcinoma

1. Progression-free and overall survival was comparable in both the intervention and control groups. 2. Serious adverse events were more common among patients taking a combination of atezolizumab-cabozantinib than cabozantinib-only. Evidence Rating Level: 1 (Excellent) Study Rundown: Immune checkpoint inhibitors are first-line therapy for patients with metastatic renal cell carcinoma (MRCC); however, optimal management for ....

Rating Level , Advanced Renal Cell , Between Jul , Immune Checkpoint Inhibitors , Kidney Cancer , Metastatic Renal Cell Carcinoma , Renal Cell Carcinoma , Vegf Inhibitors , Chronic Disease ,

Steve Job's son launches $200M healthcare investment fund

Reed Jobs, son of Steve Jobs, launches Yosemite with $200M to invest in oncology, partnering with hospitals, endowments and global family offices to fund therap ....

Steve Jobs , Emerson Collective Health , Reed Jobs , Digital Health , Venture Investing , Family Offices ,