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#VisualAbstract: No increase in mortality with paclitaxel-coated devices among patients with femoropopliteal disease

1. There was no significant increase in mortality between the paclitaxel-coated and control devices in both the intention-to-treat and as-treated analyses groups. Evidence Rating Level: 1 (Excellent) Study Rundown: The safety of paclitaxel-coated devices for femoropopliteal disease has been well-studied; however, a 2018 meta-analysis raised concerns about increased mortality risk with paclitaxel. This meta-analysis aimed to provide ....

Minute-medicine-inc , Rating-level , Paclitaxel-coated-devices , Peripheral-artery , Femoropopliteal-disease , Femoropopliteal-occlusive-disease , Mortality , Paclitaxel , Studygraphics ,

No increase in mortality with paclitaxel-coated devices among patients with femoropopliteal disease

1. There was no significant increase in mortality between the paclitaxel-coated and control devices in both the intention-to-treat and as-treated analyses groups. Evidence Rating Level: 1 (Excellent) Study Rundown: The safety of paclitaxel-coated devices for femoropopliteal disease has been well-studied; however, a 2018 meta-analysis raised concerns about increased mortality risk with paclitaxel. This meta-analysis aimed ....

Rating-level , Paclitaxel-coated-devices , Peripheral-artery , Claudication , Femoropopliteal-disease , Interventional-radiology , Paclitaxel , Paclitaxel-coated-device , Peripheral-arterial-disease , Peripheral-vascular-disease , Vascular-surgery

Neoadjuvant Nivolumab Plus Carboplatin/Paclitaxel Elicits High pCR Rates in Early-Stage TNBC

Neoadjuvant nivolumab and non–anthracycline containing chemotherapy produced promising pathologic complete response rates regardless of whether nivolumab was administered before or during treatment with carboplatin and paclitaxel in patients with stage I to IIB triple-negative breast cancer.
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San-antonio , Texas , United-states , Antonio-breast-cancer , Immunotherapy , Sabcs , San-antonio-breast-cancer-symposium , Neoadjuvant-nivolumab , Carboplatin , Paclitaxel , Breast-cancer

Lack of Vitamin D May Increase Chemo-Induced Neuropathy Risk in Breast Cancer

Investigators note that prospective research is needed to confirm the efficacy of vitamin D supplements in preventing chemotherapy-induced peripheral neuropathy in patients with breast cancer. ....

United-states , American , Axel-kock , Journal-of-the-national-comprehensive-cancer-network , Image-credit , National-comprehensive-cancer , African-american , Common-terminology-criteria , Adverse-events , Neuropathy , Vitamind-deficiency , Vitamin-d

New study challenges long-held belief about how chemotherapy works

A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and doctors have long misunderstood how some of the most common cancer drugs actually ward off tumors. ....

Danielle-ellis , Mark-burkard , National-institutes-of-health , University-of-wisconsin , Uw-carbone-cancer-center , Beth-weaver , National-institutes , Chemotherapy , Drug-discovery , Rugs , Ancer , Ell