What Makes a Vaccine's Protection Last? - Government Executive
A vaccine’s value isn’t just in its peak performance; also essential to know is when, and how quickly, protection might start to decline.
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A vaccine’s value isn’t just in its peak performance; also essential to know is when, and how quickly, protection might start to decline.
In the race to build the world’s first round of coronavirus vaccines, the spike protein—the thorny knobs that adorn each of the pathogen’s particles—was our MVP. Spike is a key ingredient in virtually every one of our current pandemic-fighting shots; it has been repeatedly billed as essential for tickling out any immune response worth its salt. “People put all their eggs in the spike basket,” Juliet Morrison, a virologist at UC Riverside, told me. And it undoubtedly paid off. In recent months, though, it’s become clear that the coronavirus is a slippery, shape-shifting foe—an...
A leading vaccine researcher on the key differences between the Moderna and Pfizer vaccines