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FASENRA met the primary endpoint in the MANDARA Phase III trial in eosinophilic granulomatosis with polyangiitis (EGPA)

First head-to-head trial of biologics in EGPA, comparing a single monthly injection of FASENRA to three injections per month of mepolizumab

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United States , United Kingdom , Michael Wechsler , Sharon Barr , Kyowa Kirin Co Ltd , American Partnership For Eosinophilic Disorders , Biowa Inc , Principal Investigator , Executive Vice President , Orphan Drug Designation , Asthma Symptoms , Deteriorating Disease , Corticosteroid Dosage , Prescribing Information , Patient Information , Churg Strauss Syndrome , Birmingham Vasculitis Activity Score , Eosinophilic Granulomatosis , Eur Respir , Allergy Clin , Very Severe Chronic Obstructive Pulmonary Disease , Frequent Exacerbations , Safety Study , Patients With Hypereosinophilic Syndrome , Zeneca Data , Glucocorticoid Sparing Effect ,

Investegate |AstraZeneca PLC Announcements | AstraZeneca PLC: Update on US review of Fasenra in nasal polyps

Investegate announcements from AstraZeneca PLC, Update on US review of Fasenra in nasal polyps ....

United Kingdom , United States , Clin Otolaryngol , Adrian Kemp , Wales National , Investor Relations Team , Biowa Inc , Kyowa Kirin Co Ltd , Drug Administration , Biologics License Application , Orphan Drug Designation , Fast Track Designation , Rare Diseases , Allergy Clin , Safety Study , Emerging Endotypes , Clin Risk , Allergy Organ , Patients With Moderate , Severe Atopic , Patients With Bullous , Very Severe Chronic Obstructive Pulmonary Disease , Frequent Exacerbations , Severe Chronic Spontaneous , Patients With Eosinophilic Esophagitis , Zeneca Data ,

First patients dosed in Phase III trials evaluating Fasenra in hypereosinophilic syndrome, eosinophilic esophagitis and eosinophilic granulomatosis

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16-Dec-2020
First patients dosed in Phase III trials evaluating Fasenra in hypereosinophilic syndrome, eosinophilic esophagitis and eosinophilic granulomatosis with polyangiitis
New clinical trial also announced for Fasenra
in eosinophilic gastritis/eosinophilic gastroenteritis
The first patients have been dosed in
Fasenra (benralizumab) Phase III trials in three rare eosinophilic diseases: hypereosinophilic syndrome (HES), eosinophilic esophagitis (EoE) and eosinophilic granulomatosis with polyangiitis (EGPA)
AstraZeneca will also initiate a Phase III trial to investigate the potential of
Fasenra in an additional rare eosinophilic disease: eosinophilic gastritis/eosinophilic gastroenteritis (EG/EGE). This trial extends the
Fasenra clinical programme to nine diseases where eosinophils play an important role, in addition to severe asthma. ....

United Kingdom , United States , Clin Otolaryngol , Bachertc Biologics , Wechslerm Akuthota , Fujiedas Imoto , Pediatr Gastroenterol Nutr , Gastroenterol Hepatol , Company On Twitter , Glob Health Epidemiol Genom , Global Health Epidemiology Reference Group , Wales National , Biowa Inc , Kyowa Kirin Co Ltd , Global Initiative For Chronic Obstructive Lung Disease , Vasculitis Foundation , Drug Administration , Impact On Health , American Academy Of Allergy Asthma Immunology , Investor Relations Team , National Organisation For Rare Disorders , J Glob Health , American Partnership For Eosinophilic Disorders , Executive Vice President , Orphan Drug Designation , Churg Strauss Syndrome ,