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Atezolizumab and Carboplatin Combo Proves Effective in Trial

Atezolizumab and Carboplatin Combo Proves Effective in Trial
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Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

Researchers at Vanderbilt-Ingram Cancer Center have discovered a druggable target on natural killer cells that could potentially trigger a therapeutic response in patients with immunotherapy-resistant, triple-negative breast cancer.

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Immunotherapy-Resistant Breast Cancer: New Vulnerability Found

Immunotherapy-Resistant Breast Cancer: New Vulnerability Found
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Vulnerability found in immunotherapy-resistant triple-negative breast cancer

Vulnerability found in immunotherapy-resistant triple-negative breast cancer
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Biomarker for breast cancer response to immunotherapy identified

Biomarker for breast cancer response to immunotherapy identified
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Biomarker shows potential to predict immunotherapy benefit for breast cancer patients

Biomarker shows potential to predict immunotherapy benefit for breast cancer patients
A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in
Clinical Cancer Research, a journal of the American Association for Cancer Research.
The study demonstrated that this biomarker, a molecule called the Major Histocompatibility Complex Class II protein (MHC-II), has the potential to be a predictor of immunotherapy benefit with two types of breast cancer -- early-stage, triple negative breast cancer (TNBC) and high-risk, estrogen receptor-positive breast cancer (HR+) when expressed on breast cancer cells. Although immunotherapies are likely to soon be prescribed along with chemotherapies for these breast cancers before surgery, most patients don't require the addition of immunotherapy to achieve treatment response. Without an optimal biomarker, clinicians don't have a reliable way to discern which patients need immunotherapy and which ones don't.

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Study identifies biomarker for breast cancer response to immunotherapy

Study identifies biomarker for breast cancer response to immunotherapy
aninews.in - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from aninews.in Daily Mail and Mail on Sunday newspapers.

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