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Clinical trial shows efficacy for atezolizumab combined with carboplatin

Clinical trial shows efficacy for atezolizumab combined with carboplatin
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Atezolizumab and Carboplatin Combo Proves Effective in Trial

Atezolizumab and Carboplatin Combo Proves Effective in Trial
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Transitional care practice helps reduce healthcare costs

A transitional care practice at Northwestern Memorial Hospital helped reduce healthcare costs compared to traditional discharge services, according to a Northwestern Medicine study published in the Journal of General Internal Medicine.

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Twin study suggests microbial influence on food allergies

Twin study suggests microbial influence on food allergies
Healthy and allergic twins exhibit distinct faecal microbial profiles, adding weight to idea that the microbiome may play a protective role in food allergies, according to a new study conducted by the University of Chicago and Stanford University,.
The study is an extension of research carried out in the Nagler laboratory at UChicago on infants' faecal microbiotas which transplanting microbes from healthy and food-allergic infants to germ-free mice and found that the healthy infant microbiota was protective against the development of food allergies.
Published in the Journal of Clinical Investigation, the current study performed an integrated microbial and metabolomic analysis of faecal samples from 18 sets of allergic and healthy twins (to be exact, both siblings had food allergy in 5 of the sets).

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Study in twins identifies fecal microbiome differences in food allergies

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A new study out of the University of Chicago and Stanford University on pairs of twins with and without food allergies has identified potential microbial players in this condition. The results were published on Jan. 19 in the
The study grew out of prior research in the Nagler laboratory at UChicago on the fecal microbiota in infants. By transplanting fecal microbes from healthy and food-allergic infants to germ-free mice (who do not possess a microbiome), investigators found that the healthy infant microbiota was protective against the development of food allergies.
"In this study, we looked at a more diverse population across a large range of ages," said Cathryn Nagler, PhD, the Bunning Family Professor in the Pritzker School of Molecular Engineering, the Department of Pathology and the College at UChicago. "By studying twin pairs, we had the benefit of examining genetically identical individuals who grew up in the same environment, which allowed us to begin to parse out the influence of genetic and environmental factors."

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